Event Title
Heart Regeneration in Carassius auratus: Histology and Response to Epinephrine
Faculty Mentor
Connie Kersten
Location
Library 7th Floor
Start Date
13-4-2013 2:45 PM
End Date
13-4-2013 3:45 PM
Description
Fish have the remarkable ability to regenerate removed tissue such as fins, scales, and internal organs. Cardiac muscle regeneration, distinct from wound healing as in mammals, has been documented in Zebrafish. This study documents early histology in goldfish (Carassius auratus) after removal of ten percent of heart muscle and its response when challenged with epinephrine. Collagen infiltration was observed by day seven and replaced by functional muscle by day 28. Heart rate increased when challenged in control and regenerated hearts over saline injected hearts. Challenged regenerated hearts had a lower heart rate than pre-challenged regenerated and pre and post-challenged controls.
Heart Regeneration in Carassius auratus: Histology and Response to Epinephrine
Library 7th Floor
Fish have the remarkable ability to regenerate removed tissue such as fins, scales, and internal organs. Cardiac muscle regeneration, distinct from wound healing as in mammals, has been documented in Zebrafish. This study documents early histology in goldfish (Carassius auratus) after removal of ten percent of heart muscle and its response when challenged with epinephrine. Collagen infiltration was observed by day seven and replaced by functional muscle by day 28. Heart rate increased when challenged in control and regenerated hearts over saline injected hearts. Challenged regenerated hearts had a lower heart rate than pre-challenged regenerated and pre and post-challenged controls.