ORCID ID

0009-0007-5659-3051

Date of Award

5-2025

Degree Type

Thesis

Degree Name

M.S.

Degree Program

Biological Sciences

Department

Biological Sciences

Major Professor

Wendy Schluchter

Second Advisor

Damon Smith

Third Advisor

Zhengchang Liu

Abstract

Additive manufacturing processes are gaining popularity for producing patient-specific biomedical equipment. For these applications, it is important that the materials are not prone to spreading infection. Herein, we examine how the fused filament fabrication process influences the morphology of surface grooves and how this affects bacterial adhesion and growth. Additionally, we made a silver nanoparticle and polylactic acid nanocomposite filament to determine its antimicrobial potential and silver ion release kinetics. For chapter three, we measured the growth of Escherichia coli and Staphylococcus aureus on polylactic acid surfaces printed with differing infill geometries and layer heights. In chapter four, we measured the silver ion concentrations released from samples made with the nanocomposite as functions of time and depth as well as the antibacterial effects of these samples. The findings of this research can be used to better understand how to manufacture objects with surfaces that inhibit microbial adhesion and growth.

Rights

The University of New Orleans and its agents retain the non-exclusive license to archive and make accessible this dissertation or thesis in whole or in part in all forms of media, now or hereafter known. The author retains all other ownership rights to the copyright of the thesis or dissertation.

Available for download on Saturday, June 01, 2030

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